Substance use disorders in bipolar patients with a painful expression - Grenoble Institut Neurociences
Communication Dans Un Congrès Année : 2023

Substance use disorders in bipolar patients with a painful expression

Julien Cabé
Xavier Moisset
Ophélia Godin
Pierre-Michel Llorca
Georges Brousse
  • Fonction : Auteur
  • PersonId : 1126529
Ludovic Samalin

Résumé

Introduction : Bipolar Disorder (BD) is a common psychiatric disease. It has been demonstrated a long time ago that bipolar patients are more painful than the healthy subjects. Substance use disorder is a frequent comorbidity in BD, but also in painful patients. The aim of our study was to analyze if bipolar patients with a painful expression have more substance use disorder than bipolar patients without pain. Objectives : The aim of our study was to analyze if bipolar patients with a painful expression have more substance use disorder than bipolar patients without pain. Methods : We included all bipolar patients from the FACE-BD cohort which is a prospective cohort of French outpatients with BD enrolled at the 12 advanced Centers of Expertise in Bipolar Disorder (CEBD). Pain has been evaluated by the “pain item” of the EQ-5D scale and we divided subjects in four categories: “no pain”, “slight pain”, “moderate pain”, “severe or extreme pain”. A multivariate analysis was performed to identify differences between each pain’s groups according to the kind of substance use disorder, psychiatric comorbidities and clinicals data. Results : The cohort enrolled 1897 bipolar patients, 970 had no pain (51.1%), 507 had slight pain (26.7%), 298 had moderate pain (15.7%) and 122 had severe or extreme pain (6.4%). We found significant differences according to age, comorbidities and clinicals data with older, more anxious, and more severe patients more represented in the more painful groups. Painful bipolar patients had also more frequently lifetime substance use disorders (alcohol, opioid, sedative, marijuana) and we were able to characterize different profiles in bipolar patients. Conclusions : Bipolar patients with a painful expression had more risks to have a lifetime substance use disorder, an anxiety disorder, and a higher score on MADRS. Interestingly, subjects seemed to prefer substances with anxiolytic or antalgic effects during the acute intoxication as alcohol, marijuana, opioid and sedatives.
Fichier principal
Vignette du fichier
substance-use-disorders-in-bipolar-patients-with-a-painful-expression.pdf (70.07 Ko) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte
licence

Dates et versions

hal-04737117 , version 1 (17-10-2024)

Licence

Identifiants

Citer

J. Chabert, Romain Icick, Julien Cabé, M.-C. Patoz, Xavier Moisset, et al.. Substance use disorders in bipolar patients with a painful expression. 31st European Congress of Psychiatry, European Psychiatric Association, Mar 2023, Paris, France. pp.S199 - S200, ⟨10.1192/j.eurpsy.2023.470⟩. ⟨hal-04737117⟩
0 Consultations
0 Téléchargements

Altmetric

Partager

More